Arthropathy in transfusional siderosis.

Transfusional siderosis and liver cirrhosis.

In the present study, cirrhosis of the liver was found in one of six cases of transfusional siderosis. The relationship between iron overload and cirrhosis is discussed and the suggestion is made that factors other than iron deposition may have been responsible for the hepatic fibrosis. Three patients with a greater degree of iron overload, and for a longer period, did not develop fibrosis or c...

Effect of inversion recovery fat suppression on hepatic R2* quantitation in transfusional siderosis.

OBJECTIVE. The purpose of this study is to evaluate whether the application of spectral pre-saturation inversion recovery (SPIR) fat suppression in standard multiecho gradient-echo sequences has a significant effect on hepatic R2* quantitation in patients with iron overload syndromes. MATERIALS AND METHODS. Eighty patients were scanned with a multiecho gradient-echo sequence without and with th...

siderosis in Bantu

SYNOPSIS Twenty-seven specimens of human tissue, obtained by operation, were tested to evaluate the theory that iron uptake by tissues from serum is greater when transferrin is nearly completely saturated than when the degree of saturation is normal. Samples of each tissue were incubated in autologous serum so prepared that in one instance the transferrin was 50% saturated and in the second 90%...

Siderosis bulbi.

Transfusional Haemosiderosis Simulating

Haemochromatosis is a disease occurring predominantly in men, and characterized by excessive deposition of iron in the tissues, coexisting with skin pigmentation and hepatic, pancreatic, and testicular fibrosis. The condition is described by Sheldon (1935) in whose monograph 311 cases are reviewed. Parenteral iron given in excess of requirements will be deposited in the tissues, since, with the...